Failure of Fourth-Generation Enzyme Immunoassay in HIV Screening and Plasma HIV-1 RNA Detection in Recent High-Risk Behavior

Acute HIV infection was not detected in a young man presenting symptoms of sexual disease infection using fourth-generation screening tests combining HIV-specific antibody and p24 antigen. Detection of plasma HIV-1 RNA concomitant with screening tests may be proposed in individuals presenting with a symptomatic sexually transmitted infection.