Hydrogel-based biomaterials are reviewed as an emerging approach to improve the delivery and viability of cells for cardiac tissue regeneration following myocardial infarction.
Hydrogels represent a promising biomaterial approach to improve cell delivery and viability for cardiac tissue regeneration after myocardial infarction.
Cardiovascular diseases remain the leading cause of death globally. Since the adult heart lacks the capacity to regenerate, loss of myocardium following myocardial infarction is irreversible and ultimately leads to failure to maintain cardiac function. In order to repopulate the areas of cell loss in the damaged hearts for restoration of cardiac function, cell transplantation/replacement has been extensively investigated. Recently, biomaterials have emerged as an approach to improve delivery and viability of cells for the regeneration of the damaged heart. Here we review the most common approaches in hydrogel-based cardiac tissue regeneration with particular focus on the implementation of hydrogels to improve cell delivery.
Sun et al. (Thu,) conducted a review in Myocardial infarction. Hydrogel-based cell delivery was evaluated. Hydrogel-based biomaterials are reviewed as an emerging approach to improve the delivery and viability of cells for cardiac tissue regeneration following myocardial infarction.
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