More advanced climacteric status at age 46 was associated with greater parasympathetic activation compared to preclimacteric women (P=0.002).
Cross-Sectional (n=2,302)
Does advanced climacteric status impact regulation of the autonomic nervous system in 46-year-old women?
An earlier-onset climacteric phase at age 46 is associated with altered autonomic regulation, specifically greater parasympathetic activation.
p-value: p=0.002
OBJECTIVE: To investigate whether an earlier-onset climacteric phase is associated with autonomic imbalance at the age of 46 years. METHODS: = 2302) groups based on menstrual history and follicle stimulating hormone values. The mean heart rate (HR), low-frequency (LF) power, high-frequency (HF) power and LF/HF ratio were analyzed from heart rate variability recordings. The variables were compared between the groups using multivariable linear regression models, including body mass index, smoking and physical activity. The effects of hormone therapy and hot flashes on autonomic function were evaluated in sub-analyses. RESULTS: = 0.002) positions compared to preclimacteric women, and the differences remained significant after the adjustments. In the sub-analyses, more frequent hot flashes were associated with a lower LF power and LF/HF ratio in the sitting position. CONCLUSIONS: The present study suggested an association between greater parasympathetic activation in women with more advanced climacteric status at the age of 46 years.
Salin et al. (Wed,) conducted a cross-sectional in Climacteric status (n=2,302). Advanced climacteric status vs. Preclimacteric status was evaluated on Autonomic function (mean heart rate, LF power, HF power, LF/HF ratio) (p=0.002). More advanced climacteric status at age 46 was associated with greater parasympathetic activation compared to preclimacteric women (P=0.002).