Determinants of Successful Implementation: A Mixed‐Methods Evaluation of a Team‐Based Telehealth Hypertension Management Program for Underserved Patients

Background Hypertension management using home blood pressure monitoring–guided pharmacotherapy is more effective than clinic‐based care, but the benefit is attenuated in underserved patients. We evaluated implementation determinants of a team‐based telehealth hypertension management program providing home blood pressure monitoring–guided pharmacotherapy and self‐management and social support. Methods We used Exploration, Preparation, Implementation and Sustainment, and Health Equity Implementation Frameworks for semistructured interviews and inductive/deductive coding using thematic analysis of qualitative data and quantitative analysis to evaluate team‐based telehealth hypertension management program implementation facilitators, barriers, acceptability, appropriateness, and feasibility. We purposefully sampled 20 patients with hypertension and 16 clinic key players from 2 safety‐net clinics in North Carolina. Quantitative measures were Acceptability of Intervention Measure, Intervention Appropriateness Measure, Feasibility of Intervention Measure, Patient Assessment of Chronic Illness Care, Organizational Readiness for Implementing Change (all measures' score ranged 1–5; higher score is better). We used concurrent embedded mixed methods (qualitative + quantitative) for convergence and complementarity. Results Five qualitative themes emerged around (1) staffing barriers, coordinated teamwork, and friendly study tools; (2) the program's patient and provider centeredness; (3) ease of home blood pressure monitoring; (4) personalized, comprehensive self‐management calls; and (5) social support. Patients and clinic key players found the program acceptable (mean±SD, 4.42±0.84 and 4.56±0.59), appropriate (4.42±0.86 and 4.61±0.50), and feasible (4.40±0.89 and 4.44±0.53), respectively. Patient Assessment of Chronic Illness Care and Organizational Readiness for Implementing Change scores were 4.22±1.01 and 4.11±0.78, respectively. Conclusions Implementing a team‐based telehealth hypertension management program depends on its tailoring to patients and providers and having their endorsement; a user‐friendly and trust‐promoting model; and having a viable financial plan. Future studies should assess clinical and cost effectiveness of the program. REGISTRATION: URL https://www.clinicaltrials.gov ; Unique identifier: NCT05424744.