Clinical and Diagnostic Determinants of Coxsackievirus Disease Severity: A Systematic Review with Comparative Analysis

Key Points

• To identify clinical and diagnostic factors that determine the severity of Coxsackievirus disease through a systematic review.
• Conducted a systematic review of literature on Coxsackievirus disease severity
• Analyzed clinical and diagnostic determinants from multiple studies
• Compared findings across various patient demographics and disease presentations
• Certain clinical factors, such as fever and rash, correlate with increased severity of disease.
• Diagnostic criteria including viral load and symptom duration are significant indicators of disease outcome.