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November 14, 2010Circulation Arrhythmia and ElectrophysiologyOpen Access

Chronic kidney disease is associated with increased atrial fibrillation prevalence, rising from 1.0% in adults without CKD to 4.2% in those with stage 4 to 5 CKD (adjusted OR 3.52).

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Why the study?

Is chronic kidney disease associated with an increased prevalence of atrial fibrillation in US adults?

Population

26,917 African-American and white US adults ≥45 years of age from the REasons for Geographic and Racial…

Comparison

Chronic kidney disease vs No chronic kidney disease

Design

Cohort

Key result

Chronic kidney disease is associated with increased atrial fibrillation prevalence, rising from 1.0% in adults without CKD to 4.2% in those with stage 4 to 5 CKD (adjusted OR 3.52).

Authors

UBUsman BaberVHVirginia J. HowardJHJonathan L. Halperin

Discussion

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Member takes

Overview

May support closer AF monitoring in advanced CKD; leaves open causality and need for prospective trials.

Structured PICO

Is chronic kidney disease associated with an increased prevalence of atrial fibrillation in US adults?

P
Population
26,917 African-American and white US adults ≥45 years of age from the REasons for Geographic and Racial Differences in Stroke (REGARDS) population-based cohort
I
Intervention
Chronic kidney disease (stage 1-2, stage 3, and stage 4-5)
C
Comparator
No chronic kidney disease (eGFR ≥60 mL/min/1.73 m² without albuminuria)
O
Outcome
Prevalent ECG-detected atrial fibrillation

Chronic kidney disease of any severity is associated with a significantly increased prevalence of atrial fibrillation among US adults.

Cite This Study

Baber et al. (2010) studied this question. Chronic kidney disease is associated with increased atrial fibrillation prevalence, rising from 1.0% in adults without CKD to 4.2% in those with stage 4 to 5 CKD (adjusted OR 3.52).

synapsesocial.com/papers/6a098deb87ad1657d2517292https://doi.org/10.1161/circep.110.957100
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