Hemodialysis patients had a significantly higher systolic dyssynchrony index (7.93 ± 2.50) compared to renal transplant recipients (3.72 ± 1.71) and healthy controls (3.00 ± 0.99, p<.001).
Cross-Sectional (n=135)
Does the systolic dyssynchrony index (SDI_16) differ between hemodialysis patients, renal transplant recipients, and healthy controls?
Hemodialysis patients exhibit higher subclinical left ventricular systolic dysfunction, as measured by the systolic dyssynchrony index, compared to renal transplant recipients and healthy controls.
Absolute Event Rate: 7.93% vs 3.72%
p-value: p=<.001
AIMS: The relationship between chronic kidney disease and development of heart failure is a well-known clinical entity. Systolic dyssynchrony index (SDI₁6) is a new diagnostic tool for detection of subclinical left ventricular (LV) systolic dysfunction by using three-dimensional echocardiography (3DE). We aimed to investigate this parameter in patients with end-stage renal disease who were receiving hemodialysis and patients with renal transplant compared to healthy control subjects. MATERIAL AND METHODS: Forty-five hemodialysis patients, 45 patients with renal transplant and 45 age-sex matched healthy control subjects included in the study. All participants were evaluated with 3DE in the interdialytic phase for measurement of LV volumes, ejection fraction and SDI₁6 parameter. RESULTS: Both LV diastolic and systolic volumes were significantly higher in hemodialysis group compared to renal transplant group and healthy controls, but this finding did not translate to a statistically significant difference for LVEF measurements between groups (58. 71 ± 3. 53 vs. 57. 17 ± 2. 97 vs. 59. 23 ± 3. 26, p =. 16 for renal transplant and hemodialysis and healthy control groups, respectively). Mean value of SDI₁6 parameters was significantly higher in hemodialysis group compared to renal transplant group (7. 93 ± 2. 50 vs. 3. 72 ± 1. 71, p <. 001) and healthy controls (7. 93 ± 2. 50 vs. 3. 00 ±. 99, p <. 001) ; whereas, it was similar between renal transplant group and control subjects (3. 72 ± 1. 71 vs. 3. 00 ±. 99, p =. 10). CONCLUSION: SDI₁6 was significantly higher in hemodialysis patients compared to patients with renal transplant and healthy controls.
Ekmekçi et al. (Sun,) conducted a cross-sectional in End-stage renal disease (n=135). Hemodialysis vs. Renal transplant and healthy controls was evaluated on Systolic dyssynchrony index (SDI_16) (p=<.001). Hemodialysis patients had a significantly higher systolic dyssynchrony index (7.93 ± 2.50) compared to renal transplant recipients (3.72 ± 1.71) and healthy controls (3.00 ± 0.99, p<.001).