What does this research mean for the field?

Recurrent cervical squamous cell carcinoma can present exclusively as pleural metastasis, which can be detected during tumor surveillance using 18F-FDG PET/CT. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to investigate pleural metastasis as a standalone presentation of recurrent cervical carcinoma using 18F-FDG PET/CT imaging.

May 20, 2026Clinical Nuclear Medicine0 citations

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Pleural Metastasis as the Only Presentation of Recurrent Cervical Carcinoma on 18F-FDG PET/CT

JCJunjun ChengSichuan University HYHui YuanCentral South University MSMinggang SuSichuan University

Key Points

This research aims to investigate pleural metastasis as a standalone presentation of recurrent cervical carcinoma using 18F-FDG PET/CT imaging.
Patient underwent 18F-FDG PET/CT for tumor monitoring due to increased serum CA-125 levels.
CT-guided biopsy was performed to confirm pathology of identified pleural foci.
Imaging revealed multiple left pleural foci and nodular thickening.
PET/CT identified multiple pleural foci, confirmed as metastases from cervical carcinoma.
Pathological examination following biopsy validated the PET/CT findings.
Increased serum CA-125 correlated with detected metastatic sites.

Abstract

A 60-year-old woman with cervical squamous cell carcinoma received 18 F-FDG PET/CT for tumor surveillance because of increased serum CA-125. PET/CT images showed multiple left pleural foci and nodular thickening of the pleura at the corresponding sites. Then, the pathology after CT-guided biopsy confirmed that the pleural foci were metastases from the cervical carcinoma.

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Pleural Metastasis as the Only Presentation of Recurrent Cervical Carcinoma on 18F-FDG PET/CT

Key Points

Abstract

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