The role of Health Technology Assessment (HTA) is evolving.Once seen primarily as a gatekeeper, HTA is increasingly viewed as a potential shaper of health system transformation.The first plenary session of the HTA International 2025 Annual Meeting, explored the potential for HTA to adopt this broader role.Drawing on perspectives from across the globe, it was discussed how HTA can help shape more equitable, responsive, and sustainable health systems by informing benefit package design, supporting universal health coverage, and addressing systemic inequities from a societal perspective.Audience polling and live commentary underscored a shared sense of urgency, as well as recognition of the methodological, political, and practical constraints to this evolution.Rather than a binary choice, a continuum of roles was suggested depending on the context in which HTA is applied.Ultimately, HTA can shape health systemsnot through ambition alone, but through evidence-informed, inclusive, and context-aware decision-making.
Oortwijn et al. (Mon,) studied this question.