Patients with intraventricular conduction defects had a five-year survival rate of 45.5%, which was significantly worse than age- and sex-matched controls.
Cohort (n=325)
No
Does the presence of intraventricular conduction defects (LBBB or RBBB with axis deviation) affect 5-year survival compared to matched controls?
Patients with intraventricular conduction defects have significantly worse 5-year survival compared to matched controls, highlighting the need to understand specific causes of death in this population.
All 42,000 electrocardiograms taken at the University of Oregon Health Sciences Center from 1969 through 1971 were reviewed; 325 patients (0.77%) had left bundle-branch block (LBBB) or right bundle-branch block (RBBB) with axis deviation (AD). In December 1974, 90% were contacted or found to be dead. The five-year survival rate (actuarial technique) (mean ± SE) was 45.5 ± 2.9%. It was significantly worse than that of age- and sex-matched "controls." In most patients the cause of death could not be determined. Survival of 164 LBBB patients (40.7 ± 4.1%) at five years was not significantly worse than that of 161 RBBB and AD patients (49.5 ± 4.2%). Those with syncope did no worse in terms of survival than did those without. The five-year survival in coronary artery disease patients was 33.7 ± 4.4%; in those with primary conduction system disease (20% of patients), it was 50.6 ± 6.6%. It will be necessary to know the causes of death and of syncope in conduction disease patients before it can be determined whether or not pacemakers can prevent either. (Arch Intern Med138:30-35, 1978)
ジョン・H・マカナウティ（サン）が325人の心室内伝導障害のコホートを行いました。心室内伝導障害と年齢・性別を一致させた対照群との比較が5年生存率で評価されました。心室内伝導障害の患者の5年生存率は45.5%であり、年齢・性別を一致させた対照群よりも有意に低かったです。
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