Cardiac PET/CT and PET/MR imaging procedural recommendations were established by the EACVI and EANM to standardize diagnosis and management of inflammatory, infective, infiltrative, and innervation cardiovascular diseases.
This document establishes standardized procedural recommendations for cardiac PET/CT and PET/MR imaging in inflammatory, infective, infiltrative, and innervation-related cardiovascular diseases.
Abstract With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with dysfunctional innervation (4Is). This standard should be applied in clinical practice and integrated in clinical (multicenter) trials for optimal procedural standardization. A major focus is put on procedures using 18 FFDG, but 4Is PET radiopharmaceuticals beyond 18 FFDG are also described in this document. Whilst these novel tracers are currently mainly applied in early clinical trials, some multicenter trials are underway and we foresee in the near future their use in clinical care and inclusion in the clinical guidelines. Finally, PET/MR applications in 4Is cardiovascular diseases are also briefly described. Diagnosis and management of 4Is-related cardiovascular diseases are generally complex and often require a multidisciplinary approach by a team of experts. The new standards described herein should be applied when using PET/CT and PET/MR, within a multimodality imaging framework both in clinical practice and in clinical trials for 4Is cardiovascular indications.
Slart et al. (2020) conducted a review in Inflammatory, infective, infiltrative, and innervation (4Is)-related cardiovascular diseases. Cardiac PET/CT and PET/MR imaging was evaluated. Cardiac PET/CT and PET/MR imaging procedural recommendations were established by the EACVI and EANM to standardize diagnosis and management of inflammatory, infective, infiltrative, and innervation cardiovascular diseases.