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March 1, 1997The American Journal of Surgical Pathology

Dedifferentiated liposarcomas exhibited a local recurrence rate of 41%, a metastatic rate of 17%, and disease-related mortality of 28%, with retroperitoneal location being the most important prognostic factor for worse survival.

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Population

155 cases of dedifferentiated liposarcoma, median age 61.5 years (range 21-92 years).

Design

Case_series

Authors

WHWalter H. HenricksYCYoung Chae ChuJGJohn R. Goldblum

Discussion

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Overview

Emphasizes retroperitoneal location for risk stratification; hypothesis-generating for expanded criteria including low-grade dedifferentiation.

Structured PICO

P
Population
155 cases of dedifferentiated liposarcoma, median age 61.5 years (range 21-92 years).
O
Outcome
Outcome and behavior including local recurrence rate, metastatic rate, and disease-related mortality.hard clinical

Dedifferentiated liposarcoma behaves as a high-grade sarcoma, and its definition should be expanded to include tumors with low-grade dedifferentiation, which may represent a precursor lesion.

Cite This Study

Henricks et al. (1997) studied this question.

synapsesocial.com/papers/6a10195301be78fe81606ad9https://doi.org/10.1097/00000478-199703000-00002
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