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April 28, 2013Statistics in Medicine63 citations

Goodness‐of‐fit test for proportional subdistribution hazards model

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BZBingqing ZhouArmy Medical UniversityJFJason P. FineUniversity of North Carolina at Chapel HillGLGlen LairdFlorida State University

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Abstract

This paper concerns using modified weighted Schoenfeld residuals to test the proportionality of subdistribution hazards for the Fine-Gray model, similar to the tests proposed by Grambsch and Therneau for independently censored data. We develop a score test for the time-varying coefficients based on the modified Schoenfeld residuals derived assuming a certain form of non-proportionality. The methods perform well in simulations and a real data analysis of breast cancer data, where the treatment effect exhibits non-proportional hazards.

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Cite This Study

Zhou et al. (2013) studied this question.

synapsesocial.com/papers/6a10951e10ed65f1d0fd08a8https://doi.org/10.1002/sim.5815
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