More frequent annual vacations were associated with a reduced risk of all-cause mortality over a 9-year follow-up in middle-aged men at high risk for CHD (RR 0.83; 95% CI 0.71-0.97).
Cohort (n=12,338)
Does more frequent annual vacationing reduce all-cause and cause-specific mortality in middle-aged men at high risk for CHD?
Taking more frequent annual vacations is associated with a significantly reduced risk of all-cause and CHD mortality in middle-aged men at high risk for cardiovascular disease.
Effect estimate: RR 0.83 (95% CI 0.71-0.97)
OBJECTIVE: The objective of this study was to determine the risk for various causes of posttrial death associated with vacation frequency during the Multiple Risk Factor Intervention Trial (MRFIT). METHODS: Middle-aged men at high risk for coronary heart disease (CHD) were recruited for the MRFIT. As part of the questionnaires administered during the first five annual visits, men were asked whether they had had a vacation during the past year. For trial survivors (N = 12,338), the frequency of these annual vacations during the trial were used in a prospective analysis of posttrial all-cause and cause-specific mortality during the 9-year follow-up period. RESULTS: The relative risk (RR) associated with more annual vacations during the trial was 0.83 (95% confidence interval CI, 0.71-0.97) for all-cause mortality during the 9-year follow-up period. For cause of death, the RRs were 0.71 (95% CI, 0.58-0.89) and 0.98 (95% CI, 0.78-1.23) for cardiovascular and noncardiovascular causes, respectively. The RR was 0.68 (95% CI, 0.53-0.88) for CHD (including acute myocardial infarction). These associations remained when statistical adjustments were made for possible confounding variables, including baseline characteristics (eg, income), MRFIT group assignment, and occurrence of a nonfatal cardiovascular event during the trial. CONCLUSIONS: The frequency of annual vacations by middle-aged men at high risk for CHD is associated with a reduced risk of all-cause mortality and, more specifically, mortality attributed to CHD. Vacationing may be good for your health.
Gump et al. (Fri,) conducted a cohort in High risk for coronary heart disease (CHD) (n=12,338). More annual vacations vs. Fewer annual vacations was evaluated on All-cause mortality (RR 0.83, 95% CI 0.71-0.97). More frequent annual vacations were associated with a reduced risk of all-cause mortality over a 9-year follow-up in middle-aged men at high risk for CHD (RR 0.83; 95% CI 0.71-0.97).
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