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September 1, 2023ClinicoEconomics and Outcomes Research5 citationsOpen Access

Examining the Burden of Potentially Avoidable Heart Failure Hospitalizations

MZMarya D. ZilberbergBNBrian H. NathansonKSKate Sulham

Key Result

Low-severity short-stay heart failure patients had significantly lower hospital mortality (0.2% vs 1.5%, p<0.001) and 30-day readmissions (8.1% vs 10.5%) compared to high-severity patients.

Key Points

  • This research investigates the characteristics and outcomes of low-severity heart failure hospitalizations to identify avoidable cases.
  • Retrospective cohort study using the Premier Healthcare Database from 2016-2021.
  • Heart failure was defined using an administrative code algorithm categorizing patients as either low or high severity.
  • Baseline characteristics and outcomes were compared between low-severity and high-severity heart failure patients.
  • Out of 301,672 short-stay CHF patients, 135,304 (44.8%) were classified as low-severity (CHF-L).
  • CHF-L patients had a lower hospital mortality rate of 0.2% compared to 1.5% in high-severity (CHF-H) patients (p < 0.001).
  • 30-day readmissions were significantly lower in CHF-L at 8.1% compared to 10.5% in CHF-H (p < 0.001).

Study Design

Type

Cohort (n=301,672)

Multicenter

Yes

Structured PICO

What are the characteristics, processes of care, and outcomes of low-severity versus high-severity short-stay heart failure hospitalizations?

P
Population
301,672 short-stay (≤ 4 days) patients admitted for congestive heart failure (CHF) in the US Premier Healthcare Database (2016-2021)
I
Intervention
Low-severity CHF (CHF-L)
C
Comparator
High-severity CHF (CHF-H), defined by cardiogenic shock, need for respiratory or circulatory support, and/or a Charlson comorbidity index >2
O
Outcome
Hospital mortality and CHF-related 30-day readmissionshard clinical

Nearly half of short-stay heart failure hospitalizations are low-severity admissions primarily for fluid management, representing a potential target for admission avoidance and cost savings.

Main Result

Absolute Event Rate: 0.2% vs 1.5%

p-value: p=<0.001

Abstract

Background: Two-thirds of the 1 million annual US CHF hospitalizations are for diuresis only; some may be avoidable. We describe a population of low-severity short-stay (2. We compared baseline characteristics, processes of care, and outcomes in low-severity (CHF-L) to CHF-H. Results: Among 301,672 short-stay CHF patients, 135,304 (44.8%) were CHF-L. Compared to CHF-H, CHF-L was younger (70.5 ± 14.1 vs 72.1 ± 13.6 years, p < 0.001), more commonly female (48.6% vs 45.8%, p < 0.001), and more likely to receive IV ACE-I/ARB agents (0.5% vs 0.4%, p = 0.003). Most other IV medications were more common in CHF-H, and anticoagulation was the most prevalent non-diuretic IV therapy in both groups (23.8% vs 33.3%, p < 0.001). Hospital mortality (0.2% vs 1.5%, p < 0.001) and CHF-related 30-day readmissions (8.1% vs 10.5%, p < 0.001) were lower in CHF-L than CHF-H. Conclusion: Among short-stay CHF patients, nearly ½ meet criteria for CHF-L, and are mainly admitted for fluid management. Avoiding these admissions could result in substantial savings.

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Cite This Study

Zilberberg et al. (2023) conducted a cohort in Congestive Heart Failure (n=301,672). Low-severity CHF (CHF-L) vs. High-severity CHF (CHF-H) was evaluated on Hospital mortality (p=<0.001). Low-severity short-stay heart failure patients had significantly lower hospital mortality (0.2% vs 1.5%, p<0.001) and 30-day readmissions (8.1% vs 10.5%) compared to high-severity patients.

synapsesocial.com/papers/6a11c0496229a93195178f66https://doi.org/10.2147/ceor.s423868
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