Polyherbal gel formulations are gaining importance in dermatological applications due to their natural origin, safety, and better patient acceptability. The present study focuses on the formulation and evaluation of a polyherbal gel containing extracts of Azadirachta indica (Neem), Ocimum sanctum (Tulsi), and Aloe vera. These herbal drugs are well known for their antimicrobial, anti-inflammatory, soothing, and wound healing properties, which make them suitable for skin care applications. In this study, herbal extracts were prepared and incorporated into a gel base using Carbopol 934 as the gelling agent. Suitable excipients were added to improve the stability, consistency, and ease of application of the formulation. The prepared gel was evaluated for various parameters such as pH, viscosity, spreadability, homogeneity, and stability. The results showed that the formulated gel had a smooth texture, uniform consistency, and good spreadability. The pH of the formulation was found to be compatible with skin. The gel also showed satisfactory stability under normal conditions. Thus, the developed polyherbal gel can be considered a safe, stable, and effective topical formulation for the treatment of common skin problems such as acne, irritation, and mild infections.
M. S. Namrata Jagtap1, Harshada Bhaskar Bankar*2, Radhika Devgore3 (Fri,) studied this question.