A logistic regression model using a subset of biosignal vital signs effectively detected acute mental stress induced by the Mannheim Multicomponent Stress Test with an F1 score of 0.82.
Observational (n=60)
No
Does acute mental stress induction using the Mannheim Multicomponent Stress Test produce measurable changes in biosignals and biomarkers in healthy adults?
A multimodal approach combining specific biosignals like QT variability and skin conductance can effectively quantify the physiological response to acute mental stress.
Numerous vital signs are reported in association with stress response assessment, but their application varies widely. This work provides an overview over methods for stress induction and strain assessment, and presents a multimodal experimental study to identify the most important vital signs for effective assessment of the response to acute mental stress. We induced acute mental stress in 65 healthy participants with the Mannheim Multicomponent Stress Test and acquired self-assessment measures (Likert scale, Self-Assessment Manikin), salivary α-amylase and cortisol concentrations as well as 60 vital signs from biosignals, such as heart rate variability parameters, QT variability parameters, skin conductance level, and breath rate. By means of statistical testing and a self-optimizing logistic regression, we identified the most important biosignal vital signs. Fifteen biosignal vital signs related to ventricular repolarization variability, blood pressure, skin conductance, and respiration showed significant results. The logistic regression converged with QT variability index, left ventricular work index, earlobe pulse arrival time, skin conductance level, rise time and number of skin conductance responses, breath rate, and breath rate variability (F1 = 0.82). Self-assessment measures indicated successful stress induction. α-amylase and cortisol showed effect sizes of -0.78 and 0.55, respectively. In summary, the hypothalamic-pituitary-adrenocortical axis and sympathetic nervous system were successfully activated. Our findings facilitate a coherent and integrative understanding of the assessment of the stress response and help to align applications and future research concerning acute mental stress.
Ernst et al. (Thu,) conducted a observational in Healthy (Acute mental stress) (n=60). Mannheim Multicomponent Stress Test (MMST) vs. Baseline rest was evaluated on Detection of acute mental stress using a subset of biosignal vital signs (F1 score). A logistic regression model using a subset of biosignal vital signs effectively detected acute mental stress induced by the Mannheim Multicomponent Stress Test with an F1 score of 0.82.