In people with chronic schizophrenia in inpatient rehabilitation wards, the prevalence of metabolic syndrome was 37.8%, with BMI ≥24 kg/m² being the strongest risk factor for ≥4 MetS components (OR 15.621, p<0.001).
Cross-Sectional (n=357)
Yes
What is the prevalence and what are the predictors of metabolic syndrome in people with chronic schizophrenia in inpatient rehabilitation wards?
In patients with chronic schizophrenia in inpatient rehabilitation, the prevalence of metabolic syndrome is high (37.8%), strongly driven by overweight status and older age, while physical activity serves as a protective factor.
BACKGROUND: Atypical antipsychotic medications increase the risk of developing metabolic syndrome (MetS) and cardiovascular diseases in people with schizophrenia. AIM: To explore the prevalence of MetS and the predictors associated with the number of MetS components in people with chronic schizophrenia. METHODS: We recruited 357 participants from 10 rehabilitation wards in northern Taiwan. The Beck Anxiety Inventory, Beck Depression Inventory-II, Health-Promoting Lifestyle Profile (HPLP), and modified Baecke physical activity questionnaire were used to evaluate the participants. MetS prevalence was calculated using the modified Adult Treatment Panel III criteria for Asians. RESULTS: The prevalence of MetS in this sample was 37.8%. Multinomial logistic regression revealed that the HPLP-exercise score (odds ratio OR = 0.411, p = .002) and depressive symptoms (OR = 0.949, p = .040) were protective factors for ≥4 MetS components. The leisure physical activity level (OR = .536, p = .024) was a protective factor for three MetS components. Body mass index ≥24 kg/m(2) was the strongest risk factor for two MetS components (OR = 8.057, p 40 (OR = 3.638, p = .012) was a risk factor for ≥four MetS components. CONCLUSION: In this study, the prevalence of MetS was higher than that reported for patients utilizing community-based services in Taiwan. The important risk factors for MetS were being overweight and older than 40. The protective factors for MetS were a high HPLP-exercise score and leisure-based physical activities.
Yang et al. (Mon,) conducted a cross-sectional in Chronic schizophrenia (n=357). In people with chronic schizophrenia in inpatient rehabilitation wards, the prevalence of metabolic syndrome was 37.8%, with BMI ≥24 kg/m² being the strongest risk factor for ≥4 MetS components (OR 15.621, p<0.001).