Research Letter: Prognostic impact of MRI-derived indexed left ventricular end-diastolic volume (LVEDVi) in individuals with preserved and reduced LV ejection fraction without heart failure in the UK Biobank

Key Points

• This research examines the prognostic role of MRI-derived LVEDVi in individuals with preserved and reduced LV ejection fraction without heart failure.
• Utilized MRI data from the UK Biobank to assess left ventricular volumes.
• Analyzed the relationship between indexed LVEDVi and cardiovascular outcomes.
• Higher LVEDVi is associated with worse cardiovascular outcomes in individuals with preserved ejection fraction.
• In those with reduced ejection fraction, LVEDVi also predicts adverse cardiovascular events.