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January 1, 1984Nucleic Acids Research75 citationsOpen Access

Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats

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JSJohn C. SchimentiCDCraig H. Duncan

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Abstract

Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.

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Cite This Study

Schimenti et al. (1984) studied this question.

synapsesocial.com/papers/6a195e75001a20a9c0d95c56https://doi.org/10.1093/nar/12.3.1641
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