What is the clinical evidence from this study?

Study design: Observational. Population: Myocardial Infarction (n=100). Primary outcome: Prevalence of psychiatric depression.

July 14, 2022Open Access

The Relationship Between Incidence of Depression After Myocardial Infarction (MI)

AGAlireza GheiniLorestan University of Medical Sciences APAli PooriaLorestan University of Medical Sciences APAfsoun PouryaTehran University of Medical Sciences

Key Result

Among 100 patients evaluated 16-18 months after myocardial infarction, 54% exhibited psychiatric depression, with the highest prevalence occurring in patients with anterior septal MI.

Study Design

Type

Observational (n=100)

Multicenter

Structured PICO

Population

100 patients with a history of myocardial infarction (diagnosed by ECG and enzymes) referred to a psychiatric center, assessed 16-18 months post-MI. Exclusion criteria: severe chronic diseases like malignancy, family history of depression or other psychiatric disorders, taking SSRIs, history of postpartum depression.

Outcome

Prevalence of depression and other psychiatric disorders evaluated using the Minnesota Multiphasic Personality Inventory (MMPI) questionnairepatient reported

There is a high prevalence of depression (54%) and other psychiatric comorbidities among patients 16-18 months post-myocardial infarction, highlighting the need for psychological rehabilitation in this population.

Limitations

Did not use more clinically applicable tests with greater reliability like PHQ-9 and GAD-7
Did not evaluate therapeutic outcomes
Did not include a control group
Data on the mental state of patients before MI was not known

Abstract

Objective: Depression is predicted to be the leading cause of mortality and morbidities in the next few years. Its association with cardiovascular diseases is well-established from various researches. The aim of this study is to evaluate the incidence of depression of co-morbid psychiatric disorders among patients with a recent history of myocardial infarction (MI). Methods: In this retrospective study, patients with a history of myocardial infarction marked by electrocardiographic (ECG) and enzymatic findings referred to our psychiatric center were included. The MMPI questionnaire was used to evaluate the prevalence of depression along with other psychiatric disorders. SPSS v18 was used to evaluate the data recorded and analyzed from these questionnaires. Results: Of 50 patients studied, the prevalence of depression is the greatest (63%) in patients with anterior septal MI. Furthermore, 26% of women and 24% of men with depression and hysteria were the common comorbidity reported. To it, 15 patients aged 60-69 years had post-MI depression. Conclusion: Our study reports an increased incidence of post-MI depression in the general targeted population. Further investigation and therapeutic measures can decrease future repercussions and the incidence of other cardiovascular events, including recurrent MI.

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