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Article1 September 1933THE EVIDENCE FOR A CEREBRAL VASCULAR MECHANISM IN EPILEPSYWILDER PENFIELD, M.D., F.R.C.S.C.WILDER PENFIELD, M.D., F.R.C.S.C.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-7-3-303 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe mechanism of so prevalent a curse as epilepsy must necessarily interest every physician. The suggestion that vasoconstriction plays a rôle in the spread of an epileptic discharge is to be found in the prescient writings of Hughlings Jackson1and he himself reported vasoconstriction in retinal arteries during an epileptic seizure. Spielmeyer2has found histological evidence of recurring vasospasm in the brains of epileptic patients. Foster Kennedy reported visible shrinking of the brain in an epileptic attack seen at the operating table and Foerster,3who has observed many fits during intracranial operations, reports that the brain shrinks, then expands enormously...1. The selected writings of John Hughlings Jackson, 1931, Ed. Taylor, London. Google Scholar2. SPIELMEYER W: The anatomic substratum of the convulsive state, Arch. Neurol. and Psychiat., 1930, xxiii, 869. CrossrefGoogle Scholar3. FOERSTERSPIELMEYER OW: Die Pathogenese des epileptischen Krampfanfalles, Deutsch. Ztschr. f. Nervenh., 1926, xciv, 15. CrossrefGoogle Scholar4. COBBFINESINGER SJ: Cerebral circulation. XIX. The vagal pathway of the vasodilator impulses, Arch. Neurol. and Psychiat., 1932, xxviii, 1243. CrossrefGoogle Scholar5. CHOROBSKIPENFIELD JW: Cerebral vasodilator nerves and their pathway from the medulla oblongata with observations on the pial and intracerebral vascular plexus, Arch. Neurol. and Psychiat., 1932, xxviii, 1257. CrossrefGoogle Scholar6. PENFIELD W: Intracerebral vascular nerves, Arch. Neurol. and Psychiat., 1932, xxvii, 30. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Montreal,*Read before the American College of Physicians, Montreal, February 9, 1933. 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H. E. Syndrome Hemiconvulsions, Hemiplegia, EpilepsyInnervation der HirnhäutePathologische Anatomie der Spinal- und Hirnnervenganglien, einschließlich der WurzelnervenBIBLIOGRAPHYCerebral Blood Flow and Electrical Corticogram preceeding and during Cardiazol Convulsion in Man and Cat.Practical Aspects of Epilepsy (With Special Consideration of Epilepsy in Children)Encephalitisartige Hirnbefunde bei plötzlichen TodesfällenDer Epileptische Anfall im Krankheits-Bild der Genuinen EpilepsieDas Syndrom des Angiospasmus der Art. ascendentesHemiconstriction of the vascular system associated with cerebral diseaseLITERATURE REFERENCESDie Zirkulationsstörungen des Rückenmarks und GehirnsZirkulationsstörungen im Gehirn, eine klinische und pathologisch-anatomische Studie 1 September 1933Volume 7, Issue 3Page: 303-310KeywordsArteriesBrainEpilepsyEpileptic seizuresVasoconstriction Issue Published: 1 September 1933 PDF downloadLoading ...
Wilder Penfield (Fri,) studied this question.
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