The influence of the composition of the nutrient medium on the growth and sporulation of Heyndrickxia coagulans BJ during submerged cultivation was investigated. The logistic curve and exponential mathematical models were employed to study the kinetics of the growth and sporulation processes. The strain demonstrated maximal value of the maximum specific growth rate of 0.174 h-1 and maximum specific sporulation rate of 0.198 h-1 in nutrient medium B. The obtained culture liquids were investigated for biological activities. Three ninhydrin-positive compounds with antifungal activity and different Rf values were detected through thin-layer chromatography (Rf1 = 0.55; Rf2 = 0.07; and Rf3 = 0.81). The strain exhibited proteolytic, amylolytic and lipolytic activities.
Gaytanska et al. (Mon,) studied this question.