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June 4, 2015Journal of Clinical Hypertension117 citationsOpen Access

Effects of the DASH Diet and Walking on Blood Pressure in Patients With Type 2 Diabetes and Uncontrolled Hypertension: A Randomized Controlled Trial

TPTatiana Pedroso de PaulaLVLuciana Verçoza VianaANAlessandra T. Z. Neto

Key Result

The DASH diet combined with walking reduced 24-hour systolic ambulatory blood pressure by 12.5 mm Hg compared to 1.5 mm Hg in the control group in patients with type 2 diabetes and hypertension.

Study Design

Type

RCT (n=40)

Randomization

Computer-generated allocation system

Multicenter

No

Structured PICO

Does a DASH diet combined with increased walking reduce blood pressure in patients with type 2 diabetes and uncontrolled hypertension?

P
Population
40 outpatients with type 2 diabetes and uncontrolled hypertension (defined as office BP ≥140/90 mm Hg and daytime ABPM ≥135/85 mm Hg), BMI ≤40 kg/m2, and serum creatinine <176 mmol/L. Mean age ~62 years, conducted at a single center in Porto Alegre, Brazil.
I
Intervention
Dietary Approaches to Stop Hypertension (DASH) diet (adapted to local habits, 25-30 kcal/kg, 55% carbohydrates, 18% proteins, 27% fat) combined with advice to increase physical activity by walking at least 15 to 20 minutes per day, 5 days per week using a pedometer. Patients received twice-weekly SMS or phone calls to stimulate compliance. Duration: 4 weeks.
C
Comparator
Dietary recommendations according to American Diabetes Association guidelines (25-30 kcal/kg, 50-60% carbohydrates, 10-20% proteins, 25-30% fat) and instructions to maintain usual physical activity. Pedometer provided only in the first and last week. Duration: 4 weeks.
O
Outcome
Blood pressure values as evaluated by ambulatory blood pressure monitoring (ABPM) and office BP measurements at 4 weeks.surrogate

A 4-week lifestyle intervention combining the DASH diet and increased walking significantly reduced ambulatory blood pressure in patients with type 2 diabetes and uncontrolled hypertension.

Main Result

Absolute Event Rate: -12.5% vs -1.5%

p-value: p=<0.001

Limitations

  • Short follow-up period
  • Pedometers capture only movements of the lower body on the vertical plane
  • Small BMI reduction observed only in the intervention group
  • Short follow-up period (4 weeks)

Abstract

Data on the potential beneficial effects of combining diet and exercise on blood pressure (BP) are still scarce. A 4-week randomized controlled clinical trial was undertaken in 40 hypertensive patients with type 2 diabetes with uncontrolled blood pressure (BP) in office and daytime ambulatory BP monitoring (ABPM). Patients were assigned to follow a Dietary Approaches to Stop Hypertension (DASH) diet associated with advice to increase walking using a pedometer (intervention group) or a diet based on the American Diabetes Association recommendations (control group). The lifestyle intervention caused a greater ABPM (mm Hg) reduction in systolic 24-hour, diastolic 24-hour, nighttime systolic, daytime systolic, and daytime diastolic measurements than observed in the control group. In the intervention group there was a decrease in urinary sodium and an increase in urinary potassium, plasma aldosterone, and the number of steps per day (P<.05). The DASH diet and increased walking were associated with clinically significant reductions in ABPM values in hypertensive patients with type 2 diabetes.

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Cite This Study

Paula et al. (2015) conducted an RCT in Type 2 diabetes and uncontrolled hypertension (n=40). DASH diet and walking vs. ADA diet and usual physical activity was evaluated on Change in 24-hour systolic ambulatory blood pressure (mm Hg) (p=<0.001). The DASH diet combined with walking reduced 24-hour systolic ambulatory blood pressure by 12.5 mm Hg compared to 1.5 mm Hg in the control group in patients with type 2 diabetes and hypertension.

synapsesocial.com/papers/6a1d805b7f448865515e77d8https://doi.org/10.1111/jch.12597
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