Cardiac functional assessment using physiological self-navigation from MR image data showed a relative difference of less than 1.3% in functional parameters compared with an ECG-gated approach.
Does cardiac functional assessment using physiological self-navigation from MR image data provide accurate functional parameters compared to ECG-gated cine MRI in volunteers and patients?
Physiological self-navigation from MR image data allows for accurate cardiac functional assessment without the need for an external ECG signal.
Effect estimate: <1.3% relative difference
PURPOSE: Electrocardiogram (ECG)-gated cine MRI provides highly accurate functional assessment of the heart. Nevertheless, reliable ECG signals are not always available due to patient's electrophysiology or due to high MR field strengths. Here, a novel framework for cardiac functional assessment using physiological information is presented, which is obtained from MR image data. METHODS: Multiple long-axis slices rotated around the center axis of the left ventricle are acquired using a 2D Golden Radial acquisition scheme. This sampling approach allows for both real-time data and retrospectively reordered cine images with different temporal resolutions. Functional information from the left ventricle is used for retrospective reordering of the data to reconstruct cine images without an external ECG signal. Afterward, individual 2D cine slices are synchronized using physiological information on the mitral valve closure. The proposed approach was assessed in 15 volunteers and applied in four patients for feasibility. RESULTS: Physiological gating signals obtained with our approach show great correlation with an ECG reference signal. Functional parameters determined with the presented method show a relative difference of less than 1.3% when compared with an ECG-gated approach. CONCLUSION: It is successfully demonstrated that functional assessment of the heart is possible using physiological information obtained directly from MR image data.
Kolbitsch et al. (Mon,) conducted a other in Cardiac functional assessment (n=19). Cardiac functional assessment using physiological self-navigation from MR image data vs. ECG-gated approach was evaluated on Relative difference in functional parameters compared with an ECG-gated approach (<1.3% relative difference). Cardiac functional assessment using physiological self-navigation from MR image data showed a relative difference of less than 1.3% in functional parameters compared with an ECG-gated approach.
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