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Dried leaves of the widespread African ethnomedicinal herb Acmella caulirhiza (Asteraceae) have been phytochemically characterised. The hexane extract yielded two unsaturated alkylamides, spilanthol and a novel compound tentatively identified as N-isobutylnona-2E, 4E-dien-8-ynamide based on 1H, 13C, COSY and HETCOR spectra. The occurrence of these amides supports the validation of documented traditional usage patterns. Copyright © NISC Pty Ltd.
Crouch et al. (Wed,) studied this question.
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