March 7, 2021Social Psychiatry and Psychiatric Epidemiology24 citationsOpen Access

Total and cause-specific mortality in patients with personality disorders: the association between comorbid severe mental illness and substance use disorders

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Why the study?

Does comorbid severe mental illness or substance use disorder increase mortality in patients with personality disorders?

Population

32,885 adult patients with a personality disorder diagnosis in the Norwegian Patient Registry between 2009…

Comparison

Comorbid severe mental illness or substance use… vs Patients with PD only and the general Norwegian…

Design

Cohort

Follow-up

mean 4.0 years

Authors

AHAnne Høye BJBjarne K. Jacobsen JBJørgen G. Bramness

Discussion

Member takes

Overview

Comorbid SUD markedly elevates mortality in PD; leaves open whether integrated interventions improve outcomes in prospective studies.

Structured PICO

Does comorbid severe mental illness or substance use disorder increase mortality in patients with personality disorders?

Population

32,885 adult patients (aged 20-79 years) with a personality disorder (PD) diagnosis in the Norwegian Patient Registry between 2009 and 2015, mean age 37.3, 60% female.

Intervention

Comorbid severe mental illness (SMI) or substance use disorder (SUD)

Comparator

Patients with PD only (no SMI or SUD) and the general Norwegian population

Outcome

All-cause and cause-specific mortality (standardized mortality ratios and hazard ratios)hard clinical

Patients with personality disorders have significantly elevated mortality, which is further exacerbated by comorbid substance use disorders or severe mental illness, particularly due to unnatural causes like poisoning and suicide.

Limitations

Registered comorbidity with SMI may represent diagnostic insecurity rather than co-existing fulfilment of separate diagnostic criteria

Cite This Study

Høye et al. (2021) studied this question.

synapsesocial.com/papers/6a2061679cec6435c3990272 https://doi.org/10.1007/s00127-021-02055-3

View Full Paper

Ask AI

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March 7, 2021Social Psychiatry and Psychiatric Epidemiology24 citationsOpen Access

Total and cause-specific mortality in patients with personality disorders: the association between comorbid severe mental illness and substance use disorders

View Full Paper

Ask AI

Bookmark

Why the study?

Does comorbid severe mental illness or substance use disorder increase mortality in patients with personality disorders?

Population

32,885 adult patients with a personality disorder diagnosis in the Norwegian Patient Registry between 2009…

Comparison

Comorbid severe mental illness or substance use… vs Patients with PD only and the general Norwegian…

Design

Cohort

Follow-up

mean 4.0 years

Authors

AHAnne Høye BJBjarne K. Jacobsen JBJørgen G. Bramness

Discussion

Member takes

Overview

Comorbid SUD markedly elevates mortality in PD; leaves open whether integrated interventions improve outcomes in prospective studies.

Structured PICO

Does comorbid severe mental illness or substance use disorder increase mortality in patients with personality disorders?

Population

32,885 adult patients (aged 20-79 years) with a personality disorder (PD) diagnosis in the Norwegian Patient Registry between 2009 and 2015, mean age 37.3, 60% female.

Intervention

Comorbid severe mental illness (SMI) or substance use disorder (SUD)

Comparator

Patients with PD only (no SMI or SUD) and the general Norwegian population

Outcome

All-cause and cause-specific mortality (standardized mortality ratios and hazard ratios)hard clinical

Limitations

Registered comorbidity with SMI may represent diagnostic insecurity rather than co-existing fulfilment of separate diagnostic criteria

Cite This Study

Høye et al. (2021) studied this question.

synapsesocial.com/papers/6a2061679cec6435c3990272 https://doi.org/10.1007/s00127-021-02055-3

View Full Paper

Ask AI

Bookmark