Young depressive outpatients had significantly increased metabolic syndrome parameters, including total cholesterol (p=0.009), LDL (p=0.001), and waist circumference (p=0.003), compared to controls.
Case-Control (n=58)
Does depression increase the prevalence of metabolic syndrome parameters in young psychiatric outpatients compared to healthy controls?
Young depressive psychiatric outpatients have a significantly higher prevalence of metabolic syndrome parameters compared to healthy controls, highlighting increased cardiovascular risk in this population.
Objectives: Metabolic syndrome is a highly prevalent disorder among the general population. Studies show an even higher prevalence among psychiatric patients. Cardiovascular disease is one of the most prevalent factors responsible for excess mortality in depression. Metabolic syndrome is associated with the development of coronary heart disease and diabetes mellitus. The objective of this study was to evaluate the prevalence of Metabolic syndrome in young depression psychiatric outpatients. Methods: 30 depressive outpatients of both sex in the age group of 20-40yrs and 28 heathy, age and sex matched controls were selected and evaluated according to the National Cholesterol Education Program criteria for metabolic syndrome, with a modification of the criteria for blood pressure and fasting glucose. Results: Except fasting blood sugar (p = 0.415) and systolic blood pressure (p = 0.132), all other parameters like, total cholesterol (p = 0.009), HDL (p = 0.0001), LDL (p = 0.001) VLDL (p = 0.002) cholesterols, triacylglycerol (p = 0.002), waist circumference (p = 0.003) and diastolic blood pressure (p = 0.002) measured in depressive patients were found to be increased and statistically highly significant than controls. Conclusions: This study shows an increased prevalence of Metabolic syndrome in depression psychiatric outpatients than controls associated with the development of coronary heart disease and diabetes mellitus. The aim of this study was to evaluate the prevalence of Metabolic syndrome in depression psychiatric outpatients.
Kiran et al. (Thu,) conducted a case-control in Depression (n=58). Depression vs. Healthy, age and sex matched controls was evaluated on Metabolic syndrome parameters (cholesterol, triglycerides, waist circumference, blood pressure, fasting glucose). Young depressive outpatients had significantly increased metabolic syndrome parameters, including total cholesterol (p=0.009), LDL (p=0.001), and waist circumference (p=0.003), compared to controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: