Diffuse Systemic Sclerosis. Alfred Stengel Memorial Lecture.

s1 April 1962Diffuse Systemic Sclerosis. Alfred Stengel Memorial Lecture. W. S. Middleton, M. D. , M. A. C. P. W. S. Middleton, M. D. , M. A. C. P. Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps: //doi. org/10. 7326/0003-4819-56-4-682₂ SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe designation of a group of disorders with the common denominator of a disruption of the ground substance as collagen diseases has revived interest in the physiology, pathogenesis, pathology, and clinical significance of the connective tissue, as well as in its physical, enzymic, and physiological chemistry. Moreover, certain of these diseases have assumed a broader importance in the recognition of their systemic extension. Scleroderma, for example, can no longer be considered as purely a dermatologic disorder, since its systemic manifestations may anticipate the cutaneous lesions and exceed them in gravity. The term "diffuse systemic sclerosis" should replace the limited terms. . . This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C. (ML) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1962Volume 56, Issue 4Page: 682-682KeywordsClinical pathologyCollagen diseasesConnective tissueLesionsPathogenesisSclerodermaSystemic diseases Issue Published: 1 April 1962 PDF downloadLoading. . .