What question did this study set out to answer?

This study aims to formulate and evaluate an Aloe vera-based herbal topical gel specifically designed for wound healing applications.

June 10, 2026Open Access

Formulation and Evaluation of Herbal Based Topical Gel Containing Aloe Vera Extract For Effective Wound Healing

Key Points

This study aims to formulate and evaluate an Aloe vera-based herbal topical gel specifically designed for wound healing applications.
Formulation of gel using Carbopol 934 and Hydroxypropyl Methylcellulose as gelling agents.
Evaluation of physicochemical parameters including pH, viscosity, and antimicrobial activity.
Assessment of in-vitro diffusion and stability over time.
The optimized formulation demonstrated good stability and favorable physicochemical properties.
The Aloe vera gel showed significant antimicrobial activity and promising wound healing potential.
Sustained release behavior was observed, indicating effectiveness for topical applications.

Abstract

ABSTRACTThe present study focused on the formulation and evaluation of an Aloe vera-based herbaltopical gel for wound healing applications. Aloe vera was selected because of itsantimicrobial, anti-inflammatory, antioxidant, and wound healing properties. The herbal gelwas prepared using Carbopol 934 and Hydroxypropyl Methylcellulose as gelling agents. Theprepared formulations were evaluated for physicochemical parameters such as appearance,pH, viscosity, spreadability, extrudability, drug content, in-vitro diffusion, antimicrobialactivity, and stability. The results demonstrated satisfactory physicochemical properties, goodstability, and sustained release behavior. The optimized formulation showed promisingwound healing potential and may serve as a safe, economical, and effective alternative toconventional topical wound healing formulations.

Formulation and Evaluation of Herbal Based Topical Gel Containing Aloe Vera Extract For Effective Wound Healing

Key Points

Abstract

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