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Mimicking the masters: An artificial nucleic acid, serinol nucleic acid (SNA), formed oligomers in which natural nucleobases were tethered through its 2-amino-1,3-propanediol (serinol) scaffold. These SNA oligomers have two unique properties: their chirality is controllable by sequence design and can be inverted by reversing the sequence (see picture), and they can cross-hybridize with DNA and RNA with sufficient thermal stability.
Kashida et al. (Wed,) studied this question.