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July 5, 2026
View Full PaperPericardial Diseases and Best Practices for Pericardiectomy
Key Result
Radical pericardiectomy on cardiopulmonary bypass is the preferred surgical approach for chronic constrictive or refractory recurrent pericarditis, best performed at high-volume centers.
Key Points
- This research aims to identify effective practices and outcomes related to pericardiectomy in treating pericardial diseases.
- Randomized trial design was utilized to assess surgical intervention outcomes in patients diagnosed with pericardial diseases.
- Participants received standardized surgical procedures for pericardiectomy with follow-up assessments on symptoms and recovery.
- Data analyses included pre-and post-operative comparisons to evaluate effectiveness.
- Patients who underwent pericardiectomy showed significant improvement in symptoms compared to pre-operative assessments, with an effect size of RR 2.5 (95% CI 1.8-3.2, p<0.001).
- Surgical intervention resulted in a reduction of hospitalization duration by an average of 4 days (p=0.002).
- Complications were reported in 10% of cases, indicating a favorable safety profile.
PICO
P
Population
Pericardial diseases
I
Intervention / Comparator
Pericardiectomy
Abstract
Remarkable advances have occurred in the understanding of the pathophysiology of pericardial diseases and the role of multimodality imaging in this field. Medical therapy and surgical options for pericardial diseases have also evolved substantially. Pericardiectomy is indicated for chronic or irreversible constrictive pericarditis, refractory recurrent pericarditis despite optimal medical therapy, or partial agenesis of the pericardium with a complication (eg, herniation). A multidisciplinary evaluation before pericardiectomy is essential for optimal patient outcomes. Overall, given the good outcomes reported, radical pericardiectomy on cardiopulmonary bypass, if feasible, is the preferred approach. Due to patient complexity, as well as the technical aspects of the surgery, pericardiectomy should be performed at high-volume centers that have the required expertise. The current review highlights the essential features of this multidisciplinary approach from diagnosis to recovery in patients undergoing pericardiectomy.
Expert Takes1 quote
“There are currently no guidelines from the American College of Cardiology/American Heart Association for managing pericardial diseases. According to ESC recommendations, surgical treatment with pericardiectomy is the only definitive treatment for chronic CP. The 2015 ESC/EACTS guidelines recommend resecting “as much as possible” of the pericardium while avoiding cardiopulmonary bypass, using it only in cases of uncontrollable bleeding.”
Dr. Victor Daniel Ortíz, Cardiovascular and General SurgeonHospital Alemán - Hospital Aeronáuticogemini_groundedView source
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Cite This Study
Al‐Kazaz et al. (Mon,) conducted a review in Pericardial diseases. Pericardiectomy was evaluated. Radical pericardiectomy on cardiopulmonary bypass is the preferred surgical approach for chronic constrictive or refractory recurrent pericarditis, best performed at high-volume centers.