Limb amputation causes significant challenges for patients in achieving effective mobility and functionality through prosthetic limbs. The prosthetic socket plays a pivotal role in the success of rehabilitation. This review explores the current advancements in prosthetic socket design and fabrication, focusing on traditional techniques like casting and lamination, and emerging technologies such as 3D printing and computer-aided design (CAD). By comparing these methods, this review highlights the advantages, limitations, and suitability for different clinical needs. This article discusses the importance of pressure distribution in socket design, emphasizing the need to relieve pressure in sensitive areas to prevent skin complications. It also examines the materials used in socket fabrication, from high-density polymers to advanced composites, assessing their impact on patient comfort and prosthetic performance. Additionally, we discuss the challenges practitioners face in prosthetic care, particularly in low-resource settings, and propose potential solutions through innovative techniques and materials. Advancements in computational modeling improved socket design and validation, enhancing patient comfort and improving the overall biomechanical interaction between the prosthesis and the user. The manuscript concludes by identifying future research opportunities, particularly in personalized prosthetic design and the integration of smart materials, to further enhance the comfort, functionality, and accessibility of prosthetic sockets.
Manrique et al. (Mon,) studied this question.