Introduction of the key update points of the 2025 Canadian Association for the Study of the Liver guideline for the management of chronic hepatitis B.

The Canadian Association for the Study of the Liver and Association of Medical Microbiology and Infectious Disease Canada developed jointly the 2025 guidelines for the management of chronic hepatitis B in May 2025. The guidelines updated recommendations for universal adult HBV screening, vaccination, laboratory assessment, treatment, patient-centered care, early diagnosis, expanding antiviral treatment. Notably, the guidelines recommend reflex HDV testing and routine use of quantitative HBsAg for the decision of HBV management.