What type of study is this?

This is a Quantitative Study study.

September 17, 2025

TE-dependent observed lung T1 measured using inversion recovery radial turbo spin echo

Key Points

Observed lung T1 increased from 985ms to 1136ms at around TE=57ms, then decreased, indicating variability.
This study quantified lung T1 using inversion recovery radial TSE at multiple TIs during free breathing.
TE-dependence of lung T1 suggests significant influence from differences in T2* and T1 across lung compartments.
Understanding T1 dependency in lung imaging may enhance gradient echo sequence effectiveness for diagnosis.

Abstract

Motivation: Observed lung T1 from Look-Locker inversion recovery depends on TE due to compartments in the lungs. These differ in T2* and T1, changig visible T1 dependent on TE. Goal(s): To examine further whether this dependence is due to differences in T2' or T2. Approach: Lung T1 was quantified in volunteers using inversion recovery radial TSE at 5 TIs. rTSE was acquired in free breathing using golden angle encoding. Results: Observed lung T1 was found to increase from T1(5.7ms)=985ms±69ms up to T1=1136±168ms at about TE=57ms and subsequently decreased but with greatly increased spread at longer TEs. Impact: Observed T1 in the lungs shows a dependence on TE in gradient echo sequences due to different T2* and T1 in tissue compartments. Here, we show TE-dependence due to T2 weighting and thus compartments also differ in T2.

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Cite This Study

Triphan et al. (Tue,) studied this question.

synapsesocial.com/papers/68d4596631b076d99fa5c2f1 https://doi.org/https://doi.org/10.58530/2025/1879

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