What type of study is this?

This is a Cross-Sectional Study study.

September 17, 2025

Reproducibility of MRI-based PDFF Quantification of Liver, Pancreas, Kidney, and Paraspinal Muscle on MRI at 5 T and 3 T in NAFLD subjects

Key Points

High reproducibility of PDFF measurements was observed across 5 T and 3 T MRI in subjects with NAFLD.
Agreement of PDFF quantification across organs such as liver, pancreas, kidney, and muscle is crucial for accurate diagnosis.
MRI-based assessments of PDFF provide reliable biomarkers for early screening of NAFLD complications.
This study includes measurements from 120 individuals, enhancing the robustness of the results.

Abstract

Motivation: Since early NAFLD is reversible, early detection and intervention, progression to irreversible liver damage, and other long-term NAFLD complications should be indicated. Goal(s): Before MRI-based PDFF is performed at 5.0 T, the agreement between the PDFF measurements in the liver, pancreas, kidney, and paraspinal muscle should be determined at 3.0 T and 5.0 T. Approach: MRI-based PDFF were obtained from the liver, pancreas, kidney, and paraspinal muscle in 120 healthy and NAFLD subjects on 3.0 T MRI 1, 3.0 T MRI 2, 5.0 T MRI. Results: PDFF showed high reproducibility for all organs within the same field and across-field strength in NAFLD subjects. Impact: 5.0 T is a reliable noninvasive biomarker of PDFF measurements in abdominal organs and may be helpful for early screening of NAFLD diseases.

Bookmark

Reproducibility of MRI-based PDFF Quantification of Liver, Pancreas, Kidney, and Paraspinal Muscle on MRI at 5 T and 3 T in NAFLD subjects

Key Points

Abstract

Cite This Study

Also Consider

Also Consider