Motivation: Large field of view TSE imaging at UHF remains elusive. Goal(s): 1) Elucidate requirements needed for repetition time reduction while maintaining contrast to noise ratio (CNR). 2) Create a loss function that explicitly enforces this condition. Approach: Perform prostate and kidney TSE experiments at 7T with different repetition times and two TIAMO modes optimized for contrast and SAR calculated from a new loss function, demonstrating performance tradeoffs. Results: Reduced TR imaging using localized AMORE modes maintained prostate contrast and filled signal voids. The new contrast optimization enabled kidney acquisitions; demonstrating high scan efficiency and image quality in large FOV TSE imaging at 7T. Impact: A generalization of the AMORE method, AMORE-C, is developed that enables TSE imaging using a TR half that of standard TSE sequences. This method has minimal SAR penalties and enables large FOV imaging in the body with improved scanning efficiency.
Haluptzok et al. (Tue,) studied this question.