Purpose: To report a case of Stargardt disease diagnosed on the basis of clinical phenotype, spectral-domain optical coherence tomography (SD-OCT), and automated perimetry, in the absence of fundus fluorescein angiography (FFA) and fundus autofluorescence (FAF). Detailed ophthalmic evaluation, multimodal imaging, and functional Methods: tests were performed. A 36-year-old male presented with progressive bilateral central vision loss. Fundus Results: examination revealed characteristic yellow–white flecks and macular atrophy. OCT demonstrated ellipsoid zone disruption, outer nuclear layer thinning, and hyperreflective deposits at the level of the retinal pigment epithelium. Automated perimetry showed dense central scotomas with preserved peripheral fields. In settings wher Conclusion: e FAF and FFA are not available, a combination of clinical findings, OCT, and perimetry can provide sufficient evidence to establish a diagnosis of Stargardt disease.
Debsikdar et al. (Mon,) studied this question.