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Analysis of treatment-associated outcomes and effect of mutation status among patients in Caris CODEai clinico-genomic database. A and B, Kaplan–Meier analysis comparing posttreatment OS between patients with STK11-mutated (mut, blue lines) and STK11-wild type (wt, red lines) NSCLC treated with (A) carboplatin (no pembrolizumab) and (B) pembrolizumab (no carboplatin). C and D, Kaplan–Meier analysis comparing (C) posttreatment OS and (D) TOT between patients treated with pemetrexed (blue lines) and osimertinib (red lines) for EGFR-mut NSCLC. E and F, Kaplan–Meier analysis comparing posttreatment OS between patients with EGFR-mut (blue lines) and EGFR-wt (red lines) NSCLC treated with (E) osimertinib or (F) pemetrexed. G and H, Kaplan–Meier analysis comparing (G) posttreatment OS and (H) TOT between patients treated with fluorouracil (blue lines) and capecitabine (red lines) for colorectal cancer.
Heath et al. (Fri,) studied this question.
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