Intra-patient spatial comparison of non-metastatic and metastatic lymph nodes reveals a reduction in CD169+ macrophages within metastatic breast cancers

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Abstract

Breast cancer cells suppress the host immune system to efficiently invade the lymph nodes; however, the underlying mechanism remains incompletely understood. Here, we aimed to comprehensively characterise the effects of breast cancers on immune cells in the lymph nodes.

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Maeshima et al. (Fri,) studied this question.

synapsesocial.com/papers/68e5b27db6db64358754b791 https://doi.org/https://doi.org/10.1016/j.ebiom.2024.105271

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