Incorporating fat and spatial saturation in MR Fingerprinting

Magnetic Resonance Fingerprinting (MRF) enables fast quantitative MR imaging, and represents an opportunity to improve upon the current standard of multi-parametric MRI (mp-MRI). In this work we demonstrate how the MRF pulse sequence can be adapted to include different saturation techniques, whilst retaining accurate T1 and T2 quantification. Extended Phase Graphs (EPGs) of the sequence illustrate the effective spoiling of chemical elements, such as fat, and spatial saturation. Phantom imaging shows that T1 quantification is not significantly affected and T2 quantification remains accurate up to 100ms. As an example, the framework is tested in-vivo in the context of prostate imaging.