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MRI T2 mapping of cartilage has been shown to be useful in characterization and monitoring of osteoarthritis (OA). Compared to conventional spin echo-based sequences, the 3D dual-echo steady-state (DESS) sequence can provide faster T2 mapping. Previous works proposed 3D DESS T2 mapping in the knee using anisotropic resolution (e.g., in-plane resolution of 0.3x0.3mm2 and slice thickness of 1.5-3mm), which limits the depiction of fine structures in 3D multiplanar reformatted images. This work investigated 3D DESS T2 mapping in the knee with isotropic acquired resolution of 0.66x0.66x0.66 mm3 and used compressed sensing (CS) to accelerate the acquisition time to <5 minutes.
Shih et al. (Wed,) studied this question.