Modified dual-contrast multi-shot 3D EPI for distortion-free and fast acquisition of simultaneous MR angiography and venography (DEPSAV)

GRE-based vascular imaging suffers from the low acquisition efficiency. In this study, we presented a new 3D dual-contrast multishot-EPI based acquisition method called DESPAV for simultaneous MR angiography and venography. Full flow compensation for K-space center line and novel Center-out trajectory was implemented. A reconstruction pipeline was developed to correct for inter-shot phase errors, off-resonance induced artifact, and enable distortion-free multi-shot joint reconstruction. Preliminary results showed that DEPSAV can provide fast intracranial arterial and venous vasculature depiction with comparable contrast and image quality to 3D GRE-based TOF/SWI, while achieve ~3-fold reduction in acquisition time.