Correlation analysis of functional relationships between morphological indicators of small intestine mersis during the supply process

аdhesion disease has become a widespread disease, which for years has maintained a tendency to constant growth, and remains one of the most complex and unsolved topical problems of the functional state of the abdominal cavity. At the moment, most changes in the functioning of the gastrointestinal tract are associated with a violation of the tissue barrier during the penetration of pathogenic types of microorganisms and absorption of toxic substances, which is one of the effects of biological factors on the intestine. Understanding the structure of the body, its morphological and functional features, the ability to understand the patterns of vital and pathological processes in various organs, tissues and the whole body. At the moment, the functional connections between the immune, nervous and endocrine links in the functioning of the tissues of the peritoneum and its components during the progressive adhesion process remain incompletely investigated. At the same time, it is also important to pay attention to the behavioral characteristics of the organism. Purpose of our investigation was to investigate the correlational relationships between the morphological indicators of the mesentery of the small intestine during the experimental adhesion process. The analysis of the relationship between the body weight and BMI of the animals of the experimental group with the morphological parameters of the adhesion formations (quantity and thickness) showed a high level of correlation, and confirms the influence of intensive processes of fibrin formation on the morphometric indicators of the experimental animals. Correlation analysis between the number of detected milk spots, the thickness of detected adhesions and the total number of lymphocytes, as well as PNA+-immunologically immature and SBA+B-lymphocytes at each observation period in the animals of the experimental group during the adhesion process showed the dependence of the thickness of fibrin formations and the number of immunocompetent cells, which can be characterized as a local immune response that determines the intensity of collagen formation by the serous membranes and affects the degree of adhesion formation. The revealed correlations between antigen-presenting cells, the area of ​​collagen fibers of the 1st and 3rd types, and the total number of lymphocytes, as well as PNA+-immunologically immature and SBA+-B-lymphocytes at each observation period in the animals of the experimental group during the adhesion process, indicate the morphogenetic function of lymphocytes against the background of the growth of the protein-synthesizing function of fibroblasts, which leads to an increase in the synthesis of collagen and other components of the connective tissue matrix. On the 14th and 21st days of the study, correlations were established between the number of antigen-presenting cells and the area of ​​collagen fibers of the 1st and 3rd types at each observation period in the animals of the experimental group during the adhesion process. The presence of these correlations indicates that the morpho-functional state of the SALC lymphoid tissue associated with the serous membranes of the peritoneum is determined by the activation of one or another link of immunity. After an antigenic impact on the body, there are shifts in the direction of activation of the population of B1-lymphocytes of the mesentery of the small intestine and B2-lymphocytes, which changes the structure of the tissue barrier of the peritoneum and affects the general state of the body.