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Comprehensive Sexuality Education (CSE) is a pivotal strategy for reducing HIV/AIDS prevalence among youth in East Africa, where the growing young population presents significant challenges for effective prevention. This review examines the role of CSE in equipping young people with essential knowledge, skills, and attitudes to make informed decisions about their sexual health. We explore the importance of culturally relevant and evidence-based curricula, the impact of teacher training programmes, and the integration of CSE into both school and community settings. We highlight the crucial role of youth-friendly health services in providing accessible and confidential care and identify peer education and youth-led initiatives as key strategies for engaging and empowering young people in HIV prevention. We examine the role of economic empowerment strategies, such as microfinance and vocational training, in reducing HIV vulnerability. We discuss gender-sensitive approaches to address the unique needs of different genders, including LGBTQ+ youth. The review also explores the potential of innovative technologies and digital solutions, such as mobile health applications and social media campaigns, to enhance HIV prevention efforts. The review emphasises community engagement and support systems, policy advocacy, and research as essential components for a comprehensive response. By integrating these diverse strategies, the review underscores the need for a multi-faceted approach to effectively address HIV/AIDS among youth in East Africa, ultimately aiming to improve health outcomes and achieve sustainable prevention goals. Keywords: Comprehensive Sexuality Education (CSE), HIV/AIDS, Youth, East Africa
Kahindo W. Nyinabo (Mon,) studied this question.