Sleep and Neuroaffective Development From Early to Late Adolescence

Sleep is fundamental to human existence—especially during periods of extensive neurodevelopment such as adolescence. Importantly, poor sleep health in the transition into puberty can impact developing neural systems, contributing to the onset and maintenance of emotional disorders such as anxiety and depression. This review explores the complex interplay between sleep and neuroaffective development in adolescence, when changes in sleep architecture, circadian rhythms, and hormonal fluctuations interact with ongoing brain maturation to impact cognitive and emotional functioning. By synthesizing extant literature and charting future directions for research and intervention, this review elucidates the bidirectional associations between sleep and neuroaffective processes during puberty and highlights how sleep architecture and neurophysiology can inform our understanding of adolescent brain development. Ultimately, this article argues that promoting sleep health and addressing sleep-related challenges, especially in early adolescence, are promising strategies for enhancing well-being and fostering positive neurodevelopmental outcomes across both healthy and clinical populations.