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The analysis of professional publications regarding the clinical and epidemiological features of tuberculosis in contemporary conditions was conducted. Literature review indicates that tuberculosis remains a pressing issue in Ukraine, particularly amidst the conditions of military conflict and active hostilities. The characteristics of multidrug-resistant tuberculosis (MDR-TB) in children and adolescents from areas of drug-resistant tuberculosis infection have been studied. The onset of MDR-TB in children is often acute, while in adolescents, it tends to be insidious. Children and adolescents are particularly susceptible to the development of MDR-TB. Annually, 1.1 million patients under the age of 15 are diagnosed with tuberculosis, with approximately 700 children dying from tuberculosis daily.The features of detection and course of clinical forms of extrapulmonary tuberculosis and the profile of drug resistance of the pathogen in different age groups were analysed based on literature data. In 2022, more cases of extrapulmonary and disseminated forms of tuberculosis were registered compared to 2019 — 15.6 % and 8.1 %, respectively. Pulmonary tuberculosis was detected in 34.7 % in 2019 and 38.9 % in 2022.In contemporary conditions, the spread and development of tuberculosis are influenced by HIV infection and coronavirus disease 2019 (COVID-19). HIV infection contributes to a tuberculosis epidemic, affecting the course and outcomes of its treatment. Stigmatisation regarding COVID-19 and fear of quarantine hindered and delayed patients seeking medical care, limiting their mobility and leading to a decrease in most medical services for the diagnosis, treatment and prevention of tuberculosis.The situation in Ukraine (prevalence of HIV infection and COVID-19, military actions in the country, population migration, presence of refugees and internally displaced persons) has also contributed to the development and spread of tuberculosis, increasing the incidence and mortality rates from this disease, and progressing its burden. Among refugees, internally displaced persons and the population of territories where these individuals are located, tuberculosis, COVID-19 and HIV infection may concurrently spread.
Pikas et al. (Wed,) studied this question.