Mp08-07 Effects of Neoadjuvant Chemotherapy on Rates of Depression in Muscle Invasive Bladder Cancer

You have accessJournal of UrologyBladder Cancer: Epidemiology 0.059]; p<0.001). Odds ratio was 1.768 (95% CI 1.426, 2.192) when comparing cohorts of with and without neoadjuvant chemotherapy. There was no statistical difference in mortality (95% CI -0.012, 0.014; p=0.844) or inpatient hospitalizations 95% CI [-0.046, 0.009; p=0.191) within 3 months. There was a statistically significant increase in suicide attempts in the neoadjuvant chemotherapy group within 3 months from cystectomy (95% CI 0.002, 0.007; p=0.002]. CONCLUSIONS: Bladder cancer development with or without treatment can induce significant patient morbidity with ensuing depression. Our retrospective cohort study demonstrates neoadjuvant chemotherapy correlates to increased incidence of depression as well as suicidal attempts. Meticulous attention needs to be directed towards mental health counseling and treatment for oncologic patients. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e116 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Matthew R. DeSanto More articles by this author Frank Anne More articles by this author Stacie Deslich More articles by this author Nathan Hale More articles by this author Thomas Cato More articles by this author Clayton Davis More articles by this author Expand All Advertisement PDF downloadLoading ...