Mp43-10 Intrarenal Pressure and Flow Rate Profile Using Lithovue Elite™: Impact of Different Irrigation Systems and Working Channel Use

You have accessJournal of UrologySurgical Technology & Simulation: Instrumentation & Technology II (MP43)1 May 2024MP43-10 INTRARENAL PRESSURE AND FLOW RATE PROFILE USING LITHOVUE ELITE™: IMPACT OF DIFFERENT IRRIGATION SYSTEMS AND WORKING CHANNEL USE Lucas B. Vergamini, Willian Ito, Aaron Tverye, Quinnlyn Walcott, Holly E. Du, Mihaela E. Sardiu, Donald Neff, David Duchene, Wilson R. Molina, and Bristol Whiles Lucas B. VergaminiLucas B. Vergamini , Willian ItoWillian Ito , Aaron TveryeAaron Tverye , Quinnlyn WalcottQuinnlyn Walcott , Holly E. DuHolly E. Du , Mihaela E. SardiuMihaela E. Sardiu , Donald NeffDonald Neff , David DucheneDavid Duchene , Wilson R. MolinaWilson R. Molina , and Bristol WhilesBristol Whiles View All Author Informationhttps://doi.org/10.1097/01.JU.0001008720.96896.83.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Several models were previously developed to describe intrarenal pressure (IRP) and flow rate (FR) in endourology. This is the first study to report real-time IRPs and FRs while performing flexible ureteroscopy utilizing LithoVue Elite™(LE) (Boston Scientific®) and different irrigation systems, including automated pumps. METHODS: Using an ex vivo model of a fresh porcine kidney/ureter, IRPs were measured by LE. Various ureteroscopic settings (US) were tested according to all possible permutations between irrigation methods (IM), working channel use (WCU), and use of ureteral access sheath (UAS). IMs employed included: Single-Action Pump™ System (SAPS, Boston Scientific®), Thermedx FluidSmart™ (Stryker®), and ENDOMAT™ (Karl Storz®). Pumps were tested at 50, 100, and 150 mmHg. WCU included 1.9Fr zero-tip basket, 200 µm and 365 µm laser fibers. UAS utilized 11/13Fr, 36cm and 12/14Fr, 36cm. Each combination was tested 3 times. Information gathered for each was averaged for comparisons. RESULTS: 84 different US were tested, totaling 252 experiments. Results are shown in Table 1 and Table 2. ENDOMAT had higher IRP, but same FR compared to Thermedx at the same US for 50 and 100 mmHg (p0.9). As the diameter of the WCU increased, lower IRP and FR were observed with the pumps (p<0.01). There was significantly higher IRP while using 11/13Fr UAS compared to 12/14Fr (p<0.01). With SAPS, IRP was similar regardless of WCU, but FR decreased with the increase diameter of WCU (p=0.81 and p<0.01, respectively). CONCLUSIONS: This experiment is the first to describe the relationship between IRP, FR, and WCU with different IMs measured by LE. ENDOMAT showed higher IRP than Thermedx at 50 and 100mmHg, while SAPS has higher IRP overall. Both IRP and FR increase with higher pump pressure and decrease with higher diameter WCU. Larger UAS significantly reduces IRP. Source of Funding: This study was funded by Boston Scientic © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e696 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Lucas B. Vergamini More articles by this author Willian Ito More articles by this author Aaron Tverye More articles by this author Quinnlyn Walcott More articles by this author Holly E. Du More articles by this author Mihaela E. Sardiu More articles by this author Donald Neff More articles by this author David Duchene More articles by this author Wilson R. Molina More articles by this author Bristol Whiles More articles by this author Expand All Advertisement PDF downloadLoading ...