April 12, 2024

Fabrication of gastro-floating sustained-release etoricoxib and famotidine tablets: design, optimization , in-vitro , and in-vivo evaluation

MSMarwa SaadyAmerican University in Cairo NSNabil A. ShomanAhram Canadian University MTMahmoud H. TeaimaCairo University

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Abstract

In this study, a new gastro-floating sustained-release tablet (GFT) with a combination of Etoricoxib (ET) and Famotidine (FM) was successfully developed. GFTs were prepared by using a combination of hydrophilic swellable natural/semi-synthetic polymers as a controlled-release layer. Through a 2

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